Press releases

All Press releases are available in Swedish.

Interim report 2017-01-01 till 2017-03-31

Period (2017-01-01-2017-03-31)

  • Operating revenue KSEK 0 (0)
  • Income after financial items KSEK -1491 (-307)
  • Earnings per share -0,10 (-0,04) SEK
  • Cash and cash equivalents (2017-03-31) 31 275 (4 114) KSEK
  • Equity ratio 98,2 (97,8) % as of 2017-03-31

Significant events during first quarter of 2017 

  • The subscription period for TO 1 ended February 10, 2017 and during this period 2,405,992 warrants was exercised for an equal number of shares corresponding to a subscription rate of approximately 96%. Cyxone will thereby receive approximately SEK 12 million before issue costs.
  • Cyxone's candidate drug T20K ability to both prevent and inhibit multiple sclerosis in animal models was verified by an independent laboratory.

Significant events after the end of the period 

  • A collaboration agreement has been made with Bachem AG in Switzerland to improve the synthesis of T20 and produce drug for non-clinical and clinical studies.

CEO Kjell Stenberg comments
Immediately after New Year, Cyxone started its evaluation of the T20K results obtained under 2016. In this effort Cyxone is supported by its Scientific Advisory Board and its strategic partner Sourcia. The goal has been to design a T20K development program up to phase II clinical trials. Considerable efforts have been made to find external companies capable of delivering high-quality studies to a fair prize to meet the company's timeline.

During the period, the very promising efficacy of T20K on animal MS earlier reported has been validated by an independent laboratory. Cyxone has received confirmation that T20K can inhibit MS symptoms prophylactically (before disease induction) as well as therapeutically, i.e. when the disease symptoms have become manifest. T20K's effect on MS is comparable to that of the leading oral MS drug Gilenya.

In 2017, the company plans to study the effects on MS development in animals treated as soon as signs of disease progression occur, i.e. mirroring the plans to treat MS patients as soon as possible after diagnosis and maintain patients in remission. Other activities planned are chemical synthesis of T20K for animal studies and for man, develop and refine analytical methods, study pharmacological effects of T20K for a better safety assessment, carry out toxicity and pharamcokinetic studies (to quantify uptake, measure distribution and excretion of T20K).

Cyxone has introduced T20K and its anti-inflammatory cyclotide technology to leading pharmaceutical companies in Europe and the United States and has an ongoing positive dialogue.

We are very pleased by the strong interest by shareholders demonstrated through a 96% conversion of the company's first warrants (TO1) into shares. An additional SEK 12 million before issue costs was hence added to Cyxone.

Follow our news and information about our presence at investor meetings via First North, and the company's webpage: www.Cyxone.com
Kjell Stenberg CEO, Cyxone AB

Upcoming financial reports and Annual General Meeting
2017-05-23 General Meeting
2017-08-30 Interim report

Full report is attached.

Malmo May 16, 2017

Board of Directors 
Cyxone AB

Contact:
Cyxone AB (publ)
Kjell G. Stenberg, CEO
Tel: 0723-816168
E-post: kjell.g.stenberg@cyxone.com
Adelgatan 21
211 22 Malmö
www.cyxone.com

This year-end report is such information Cyxone AB is obligated to publish under the EU Market Abuse Regulation and Securities Markets Act. The information was released by CEO Kjell Stenberg for publication May 16, 2017 at. 08:50 CET.

This report contains forward-looking statements, consisting of subjective assumptions and forecasts for future scenarios. Predictions for the future only apply as of the date they are made and are, by their nature, as well as research and development work in the biotech segment, associated with risk and uncertainty. The actual outcome may deviate significantly from the scenarios described in this press release.

August 30, 2017
Regulatory

Summary of interim report

Period (2017-01-01-2017-06-30)

  • Operating revenue KSEK 0 (0)
  • Income after financial items KSEK -4 075 (-1 626)
  • Earnings per share -0,27 (-0,13) SEK
  • Cash and cash equivalents, KSEK 28 114 (24 636) as of 2017-06-30
  • Equity ratio 95,2 (87,9) % as of 2017-06-30

Period (2017-04-01-2017-06-30)

  • Operating revenue KSEK 0 (0)
  • Income after financial items KSEK -2 588 (-1 157)
  • Earnings per share SEK -0,17 (-0,09) 
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June 14, 2017

Cyxone signs acquisition agreement for candidate drug in Phase 2 Cyxone can announce today that the company has signed an agreement pertaining to the exclusive rights to acquire the clinical candidate drug Rabeximod from OxyPharma AB. The transaction has been structured so as to minimise the impact on Cyxone's cash flow by offering the seller 1,916,372 shares, (one million, nine hundred and sixteen thousand, three hundred and seventy two shares amounting to a dilution of 12.5 per cent), as well as royalty rights amounting to ten (10) per cent of future net earnings from Rabeximod. Cyxone will call an extraordinary general meeting to seek shareholder approval for a directed new share issue. This will pave the way for the acquisition and a Phase 2b-study in rheumatoid arthritis.

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June 07, 2017

Cyxone AB and the University of Queensland in Australia are launching a co- operation agreement to continue studies into the effects of Cyxone's T20K development substance in combating MS.

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May 18, 2017

Cyxone can announce today that it has established a long-term strategic co-operation agreement with Sourcia, a clinical contract research organization (CRO) with offices in Belgium, Germany, and the Netherlands.

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May 16, 2017
Regulatory

Period (2017-01-01-2017-03-31)

  • Operating revenue KSEK 0 (0)
  • Income after financial items KSEK -1491 (-307)
  • Earnings per share -0,10 (-0,04) SEK
  • Cash and cash equivalents (2017-03-31) 31 275 (4 114) KSEK
  • Equity ratio 98,2 (97,8) % as of 2017-03-31
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May 15, 2017

Since 2016, Cyxone AB and Swiss pharmaceutical manufacturer Bachem AG have worked closely on the production of syntheses of Cyxone's development substance T20K, and on the production of substances for studies that started last year.

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March 10, 2017
Regulatory

Cyxone can announce today that an independent research group at Monash University in Australia has confirmed the positive effects of the company's development substance T20K on multiple sclerosis (MS) symptoms in animal models as previously described.

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December 21, 2016
Regulatory

Today, Cyxone announce that they will acquire the entire family of patents protecting the Company's main candidate T20K, from the Medical University of Vienna. The cost of € 100,930 includes VAT and corresponds to the costs of the patenting process.

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December 19, 2016
Regulatory

Cyxone announce that T20K demonstrates no measurable toxic effect in mice after oral administration of up to 100 mg/kg in a single dose.  Even at an oral dose of 250 mg/kg, half of the animals recovered well after treatment. Low toxicity of injected T20K has previously been reported by Cyxone.

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November 21, 2016
Regulatory

In accordance with the regulations on Nasdaq First North Stockholm, Cyxone uses a Certified Adviser (CA).

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